Congenital nevus - 先天性痣
鼻子上的大痣若在新生兒期未予切除，日後將難以徹底去除。
由於形狀不規則，需要進行活檢。
relevance score : -100.0%
ReferencesCongenital melanocytic nevus 是一種在出生時或嬰兒期形成的胎記。Nevus sebaceous 是一種涉及毛囊缺陷的皮膚異常。在這項研究中，我們使用稱為針孔法的雷射技術以及 Erbium:YAG 雷射，治療不同患者的痣病變。
Congenital melanocytic nevus (CMN) is a melanocytic nevus that is either present at birth or appears during the latter stages of infancy. Nevus sebaceous has been described as the hamartomatous locus of an embryologically defective pilosebaceous unit. Here, we describe how we used the pinhole technique with an erbium-doped yttrium aluminium garnet (erbium : YAG) laser to treat nevi lesions in different patients.
Congenital melanocytic nevus (CMN) is a melanocytic nevus that is either present at birth or appears during the latter stages of infancy. Nevus sebaceous has been described as the hamartomatous locus of an embryologically defective pilosebaceous unit. Here, we describe how we used the pinhole technique with an erbium-doped yttrium aluminium garnet (erbium : YAG) laser to treat nevi lesions in different patients.
Giant congenital melanocytic nevus 是一種先天性皮膚黑色素痣，從出生即存在，長大後其寬度可超過 20 公分。此情況極為罕見，發生率低於每 20,000 名新生兒中 1 人。雖然罕見，但其重要性不容忽視，因為可能增加皮膚癌等嚴重併發症的風險，亦可能影響大腦與神經（神經皮膚黑變病）。一生中罹患皮膚癌的機率約為 5% 至 10%。
Giant congenital melanocytic nevus is usually defined as a melanocytic lesion present at birth that will reach a diameter ≥ 20 cm in adulthood. Its incidence is estimated in <1:20,000 newborns. Despite its rarity, this lesion is important because it may associate with severe complications such as malignant melanoma, affect the central nervous system (neurocutaneous melanosis). The estimated lifetime risk of developing melanoma varies from 5 to 10%.
Giant congenital melanocytic nevus is usually defined as a melanocytic lesion present at birth that will reach a diameter ≥ 20 cm in adulthood. Its incidence is estimated in <1:20,000 newborns. Despite its rarity, this lesion is important because it may associate with severe complications such as malignant melanoma, affect the central nervous system (neurocutaneous melanosis). The estimated lifetime risk of developing melanoma varies from 5 to 10%.
與普通黑色素細胞痣相比，先天性黑色素細胞痣的直徑通常較大，且常伴有過多毛髮。若直徑超過 40 公分（16 吋）且毛髮過多，亦稱為巨毛痣。
隨著兒童成長，黑色素細胞痣會與身體大小成比例增長，毛髮在青春期後尤其明顯。
手術切除是標準治療。許多人為了美觀而接受手術；同時，為了降低癌變風險，較大的痣也會被切除。巨大的先天性痣惡性轉變為黑色素瘤的風險較高，文獻報告的轉化率約為 2‑42%。
當病灶較小時，手術切除較為容易；但隨著年齡增長，疤痕會變大，想要在不留下疤痕的情況下完全去除變得相當困難。
○ 治療
#Staged excision (congenital nevus)